Blood Clot & Bleeding Disorders

Expert care. Effective therapies.

Receive exceptional care and treatment from our compassionate, dedicated team of hematologists and blood disorder specialists. Our highly rated programs, support services and treatment options help you improve your daily life while managing your condition. At Novant Health Hematology, you’ll work with a team of experienced hematologists who diagnose and treat even the rarest forms of bleeding disorders based on the latest research.

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Blood Clotting Disorders

What is venous thromboembolism?  

Venous thromboembolism (VTE) refers to both deep vein thrombosis (DVT) and pulmonary embolism (PE). These serious conditions are often underdiagnosed, but also are preventable and treatable.  

What causes blood clotting disorders? 

Your risk for experiencing venous thromboembolism (VTE) increases with age, obesity and a strong family history of VTE.  Other conditions putting you at higher risk include: 

  • bone fractures, severe muscle injury, major surgery 
  • bed confinement after surgery or a medical condition and limited movement (like wearing a cast or sitting for a long time) 
  • increased estrogen (birth control pills, pregnancy, estrogen replacement therapy after menopause)  
  • health conditions including heart or lung disease, cancer, cancer treatment and inflammatory bowel disease  
  • central venous catheters 

You may inherit a condition that puts you at higher risk for forming blood clots. Fortunately, the more severe conditions (protein S, Protein C and Antithrombin deficiency) are rare and the more common conditions (Factor V Leiden and Prothrombin Gene mutation) are less risky.   

Should I be tested for VTE? 

In general, you do not need to be screened for VTE unless you have a history of blood clotting for a hereditary condition. Testing for these conditions also is not a necessary part of an initial evaluation of VTE. Test results will be falsely abnormal in the case of an acute clot or during anticoagulation therapy.  A test may be helpful at the end of therapy to assist with determining the length of your treatment.   

What to expect with blood clotting treatment. 

Whether you experience a blood clot for the first time or have an inherited condition you need to manage, you’ll want expert care from a team of specialists who have access to the latest research and treatments. At Novant Health Hematology, you’ll be supported by a team of compassionate experts who work closely with you to diagnose your condition and develop an individualized care plan.  

Preventative treatment 

To prevent blood clotting and lower your risk of VTE, you may receive a low-dose anticoagulation medication following surgery, during a prolonged hospital stay or in some other high-risk situations. Sequential compression devices (SCD), cuffs worn on the legs that inflate and deflate to push blood through the veins, also reduce the risk of blood clots if you are confined to the bed. Movement is another great preventive measure. Getting up and moving around as soon as your provider allows can go a long way toward preventing VTE.   

DVT & PE treatment  

If you are diagnosed with DVT or PE, you will likely be treated with full dose anticoagulation therapy. These drugs keep the clot from continuing to grow and embolize. Anticoagulation drugs are sometimes called “blood thinners,” but they do not actually “thin” the blood. They make the blood less likely to clot and keep clots from growing.   

Standard treatment with anticoagulation therapy for a DVT and PE lasts 3 to 6 months. By the end of 3-6 months on anticoagulation therapy, the clot matures and becomes firmer. A mature or chronic clot is much less likely to progress or embolize to the lung.   

Sometimes you may need to undergo treatment to break up clots. Our vascular specialists and interventional radiologists administer these aggressive treatments for life or limb-threatening situations. While potentially lifesaving, “thrombolytic” therapies also can put you at risk of bleeding and other dangerous complications compared to standard anticoagulation medications. Our team of experts will discuss the risks and benefits of these treatments to determine the best care for you. 

If you are at high risk for another blood clotting event, you may benefit from taking anticoagulation medications for a longer period of time. We’ll work closely with you to discuss your options and understand your preferences based on careful risk assessment.  

Types of Blood Clotting Disorders

Bleeding Disorders

What is a bleeding disorder? 

If you experience abnormal bleeding or bruising either randomly or following injuries or surgery, you may have a bleeding disorder that requires medical attention. Some bleeding disorders are “acquired,” which means they are not inherited and may be due to medications or an immune system condition.    

Other bleeding conditions like hemophilia, von Willebrand disease and some rare platelet disorders are inherited or passed down from parents to their children. Sometimes, easy bruising or bleeding is caused by fragile connective tissues around blood vessels that makes them tear and leak blood into surrounding tissues. 

Diagnosing bleeding disorders 

Diagnosing why you are experiencing abnormal bleeding often takes time and patience. The hematology specialists at Novant Health go beyond traditional care, providing high-level expertise and advanced lab testing to accurately diagnose your condition and plan your care. We’ll work closely with you to solve the mysteries of your blood clotting disorder and develop an individualized treatment plan based on the latest research for medicines and procedures.  

Types of Bleeding Disorders

Nurse drawing a woman's blood for lab tests.

Understanding Your Risks

Understanding your underlying condition can help us better treat your blood disorder. Novant Health Hematology offers genetic testing to help identify the condition that may be causing you to experience abnormal platelet production. We also offer pre-conception counseling to help minimize issues for you and the fetus during your pregnancy or delivery. Our genetic counseling team can talk with you about options for testing and whether it is right for you.