Novant Health Clinical Research provides access to a variety of cardiac research
Study Name/Number: RESPOND CRT
Title: Clinical Trial of the SonRtip lead and Automatic AV-VV Optimization Algorithm in the Paradym RF SonR CRT-D
Investigator: Mark Mitchell, MD
Purpose: The objective of this study is to assess the safety and effectiveness of the automatic atrioventricular (AV) delay and interventricular (VV) delay optimization algorithm used in the PARADYM RF SONR Cardiac Resynchronization Therapy with Defibrillation (CRT-D) device (Model 9770) in combination with the SonRtip Lead, which includes a SonR sensor in the tip of the atrial pacing lead, and compatible programming software. This study will evaluate the effectiveness of the automatic optimization algorithm in increasing the rate of patients responding to the therapy as compared to an echocardiographic optimizatin method. This study will also evaluate the safety and effectiveness of the SonRtip atrial pacing lead.
Eligibility: At least 18 years old, with a class I and IIa indication for implantation of a CRT-D device, documented Moderate) Severe HF (NYHA Class III or ambulatory IV), and LVEF 35%
to the current ClinicalTrials.gov record »